What is the main cause of fibrosis

Forms of pulmonary fibrosis

The Sarcoid (Boeck's disease) is characterized by inflammation and microscopic nodules in the connective tissue, so-called granulomas. The cause of the formation of these granulomas, which then lead to impairment of organ function, has not yet been clarified. In principle, all organs of the body can be affected, and the clinical picture is correspondingly diverse. The lungs are almost always affected.

Sarcoid is most often diagnosed between the ages of 20 and 40, more often in women than men. The disease is very rare in the Mediterranean countries and Africa, but is quite common in Northern Europe.

The German Lung Foundation assumes that 70,000 to 90,000 people in this country know that they suffer from sarcoid. Since the disease can cause a variety of symptoms and is difficult to recognize, the actual number of people affected is likely to be much higher.

There is an acute form, also known as Löfgren's syndrome, and a chronic form. This accounts for more than two thirds of the cases. The chances of recovery depend on the severity of the disease, but are usually good.

To Treatment of sarcoid mostly corticosteroids - the most famous representative of which is cortisone - are used. The disease often heals spontaneously even without therapy. However, it is important to monitor whether the disease is progressing. Stage III, the “highest” stage of sarcoid, is characterized by pulmonary fibrosis with permanent damage to the lungs. With timely therapy, however, this can be prevented in almost all patients today or at least delayed for a long time.

In the chapter “Sarcoidosis” you will find further information on this clinical picture.